NONOPERATIVE Observation (if asymptomatic) Fibrous dysplasia / osteofibrous dysplasia Enchondromas / Olliers / Marfucci's Osteochondroma /MHE NOF / Jaffe-Campanacci Paget's Eosinophillic Granuloma Lipoma (soft tissue) Bisphosphonate therapy Metastatic bone disease (with wide resection and radiation) Myeloma (with chemotherapy) Paget's disease (with observation) Fibrous dysplasia (with observation) Radiation alone Solitary myeloma Chemotherapy alone Lyphoma Multiple myeloma OPERATIVE Radiofrequency ablation • Osteoid osteoma Aspiration and Injection • UBC Curretage and Bone Grafting • GCT• ABC • Chondroblastoma• Chondromyxoid fibroma• Osteoblastoma• NOF(if symptomatic) Marginal Resection • Periosteal chondroma• Neurilemoma (soft tissue) • Nodular fasciitis (soft tissue) • Epidermal inclusion cyst• Glomus tumor Wide Resection Alone • Chondrosarcoma• Parosteal osteosarcoma• Chordoma• Adamantinomma• Squamous cell (if no mets) Wide Resection + Irradiation • Metastatic Bone Disease • Soft tissue sarcoma-high grade (angiosarcoma, synovial sarcoma, liposarcoma, desmoid tumor, MFH/fibrosarcoma) Wide Resection + Chemotherapy • Osteosarcoma• Periosteal osteosarcoma• Ewing's• MFH / fibrosarcoma • Secondary sarcoma• Dedifferentiated chondrosarcoma• Rhabdomyosarcoma (exception to soft tissue sarcoma tx)