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Presence of a third-party abrasive particle
31%
47/153
Disproportionate use of the limbs by the patient
7%
10/153
Defective femoral head
0%
0/153
Method of fixation of the femoral component
19%
29/153
Method of sterilization and shelf life of the polyethylene
43%
66/153
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Over the past three decades, gamma irradiation and air has been the most common method of sterilizing polyethylene used in total joint arthroplasty. This method of sterilization results in breakage of the chemical bonds within the polymer. While this promotes cross-linking, it also leaves the polyethylene vulnerable to oxidation, especially if packaged in an air environment. Oxidation has been shown to decrease polyethylene’s molecular weight, ultimate tensile strength, elongation, and toughness which results in a stiffer, more brittle material that is less resistant to wear. Severity of oxidation and a decrease in mechanical properties have been shown to be related to the length of time that the component is exposed to air (the shelf life). Currier and associates studied the clinical performance of gamma irradiated in air polyethylene components that had been shelf aged. They demonstrated that for the first 5 years of shelf life, polyethylene oxidized rather slowly. However, polyethylene components with a shelf life of more than 5 years would be expected to have minimal mechanical toughness and would likely fail rapidly if implanted. Bohl and associates evaluated 135 patients who had undergone total knee arthroplasty. Survivorship at 5 years was 100% for components with a shelf life of less than 4 years, 89% for components with a shelf life of 4 to 8 years, and 79% for components with a shelf life of more than 8 years. Sychterz and associates reported no correlation between shelf life and true wear rates for components with a shelf life of less than 3 years. In summary, both in vivo and in vitro data suggest that shelf life in excess of 3 to 5 years has a direct effect on wear of polyethylene.
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