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Genetic drift
4%
38/1048
Expansion
1%
14/1048
Mendelian inheritance
6%
61/1048
Anticipation
86%
902/1048
Phenotypic plasticity
2%
23/1048
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Anticipation is a phenomenon whereby the symptoms of a genetic disorder become apparent at an earlier age as it is passed on to the next generation. In most cases, an increase of severity of symptoms is also noted. Anticipation is common in trinucleotide repeat disorders such as Huntington's disease, myotonic dystrophy, Friedreich ataxia, and Fragile X syndrome. Illustration A shows the genetics of the trinucleotide repeat disorders.
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