This article updates the practicing pediatrician's knowledge of the hypophophatemic disorders that may occur in children. The classic X-linked disorder is emphasized. Details of clinical manifestations, the wide spectrum of disease severity, and complications of the disorder in adults are reviewed. Recent research, new genetic findings, and speculations regarding pathophysiology are discussed. A strategy for approaching medical treatment of X-linked hypophosphatemic rickets is provided, together with complications of treatment and treatment after cessation of growth.





Polls results
1

On a scale of 1 to 10, rate how much this article will change your clinical practice?

NO change
BIG change
75% Article relates to my practice (3/4)
25% Article does not relate to my practice (1/4)
0% Undecided (0/4)
2

Will this article lead to more cost-effective healthcare?

75% Yes (3/4)
25% No (1/4)
0% Undecided (0/4)
3

Was this article biased? (commercial or personal)

0% Yes (0/4)
100% No (4/4)
0% Undecided (0/4)
4

What level of evidence do you think this article is?

0% Level 1 (0/4)
25% Level 2 (1/4)
25% Level 3 (1/4)
50% Level 4 (2/4)
0% Level 5 (0/4)