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What is the primary indication for performing an arthroscopic synovectomy on a patient with hemophilia that is the result of factor VIII deficiency?
Joint pain with radiographic evidence of joint space narrowing
Joint stiffness that has not improved with physiotherapy and bracing
Recurrent joint bleeding despite optimal medical management
Prophylaxis for joint preservation in severe hemophilia (factor VIII level <1%)
Decreasing ambulatory endurance despite optimal medical management
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To control most spontaneous bleeding into the knee in children with hemophilia, factor VIII must be replaced to what percentage of normal?
0% to 10%
20% to 30%
40% to 50%
60% to 70%
80% to 90%