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A 2-year-old boy is brought in by his mother after an unwitnessed fall. She reports the child is constantly thirsty. His clinical appearance and radiographs are shown in Figures A through D. What is the most likely diagnosis?
Langerhans cell histiocytosis
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A 6-year-old boy presented to the emergency department with a suspected head injury after a fall. His parents attribute the injury to a loss of balance as they have noticed a worsening left sided limp over the past 2 months. Radiographs of the head and pelvis are seen in Figures A and B. Further questioning revealed the child has recently been worked up for increasing thirst and non-specific abdominal pain. A histology specimen can be seen in Figure C. What is the most likely diagnosis?
A 5-year-old child presents with skin lesions and a limp. He has met all developmental milestones accordingly but his parents have noticed he has recently stopped gaining weight. Clinical photograph of his skin lesion, radiograph of his left hip, and histology slide representative of his hip lesion are shown in Figures A, B, and C respectively. What is the most likely diagnosis?
Acute lymphoblastic leukemia
A 7-year-old boy complains of pain in the right thigh for 1 month with no history of traumatic injury. A radiograph is provided in Figure A. A histology specimen from incisional biopsy is provided in Figures B and C. Which of the following is the most appropriate management?
Conservative treatment with crutches and repeat radiographs in 6 weeks
Wide excision and chemotherapy
Radiation therapy alone
Curettage and bone grafting