Innovations for Active Healing that Enhance the Body’s Ability to Heal Bioventus is a global leader of innovations for active healing. Through a combination of internal product development, product/business acquisition, and distribution agreements, we will bring to market products which address a growing need for clinically effective, cost efficient, minimally invasive medical treatments, that engage and enhance the body’s natural healing processes.

Our newly merged Orthofix-SeaSpine organization is a leading global spine and orthopedics company with a comprehensive portfolio of biologics, innovative spinal hardware, bone growth therapies, specialized orthopedic solutions, and a leading surgical navigation system. Our products are distributed in 68 countries worldwide. Our medical device company is headquartered in Lewisville, Texas, and has primary offices in Carlsbad, CA, and Verona, Italy. Our combined company’s global R&D, commercial and manufacturing footprint also includes facilities and offices in Irvine, CA; Toronto, Canada; Sunnyvale, CA; Wayne, PA; Olive Branch, MS; Maidenhead, UK; Munich, Germany; Paris, France; and São Paulo, Brazil. Founded in Verona, Italy, and now headquartered in Lewisville, Texas, Orthofix is proud to be recognized as the 8th Largest Orthopedic Medical Device Company in the World by Medical Design & Outsourcing magazine. Orthofix is committed to improving patients’ lives and delivering innovative, quality-driven solutions that empower physicians and healthcare organizations to meet the needs of their patients every day.

Carlsmed’s mission is to improve outcomes and decrease the cost of healthcare for spine surgery and beyond.

Manufacturers of Surgical Instruments Aesculap was founded in 1867 in Tuttlingen, Germany and has grown into the largest and one of the most respected manufacturers of surgical instruments in the world. Over the years, Aesculap has continued to evolve into a diversified healthcare corporation by focusing its expertise in the areas of orthopaedics, spinal implants, neurosurgery and vascular systems and sutures. B. Braun acquired Aesculap in 1996. B. Braun is a private company which was founded in 1839 in Melsungen, Germany. It is one of the world's top ten diversified medical companies with revenues in excess of $4 Billion. Aesculap is the surgical division within the B. Braun family of companies. Aesculap entered the total joint replacement market in Europe in 1972. Since then, Aesculap has grown to become the 6th largest orthopaedic implant company in the world and it continues to expand its presence. In 1980, Aesculap was one of the first companies to enter the spine market with the introduction of a revolutionary product for anterior cervical fusions, the Caspar retractor and plating system. This retractor system remains the industry's gold standard. In order to be more responsive to its growing customer base in spine and orthopaedics, Aesculap, Inc. formed a new company, Aesculap Implant Systems, Inc. This new company focuses on these unique markets allowing for greater innovation and customer service. Aesculap Implant Systems maintains a surgeon/patient focus with the goal of improved operative procedures and patient outcomes leading to an improved quality of life.

Cerapedics is a global, commercial-stage ortho-biologics company that aspires to transform the standard of care for bone repair, healing bones faster and at higher rates, without compromising safety, so that patients can live their healthiest lives. Bone grafts, including Cerapedics’ products, are used in over four million annual spine, orthopedics, trauma and interventional procedures world-wide. Cerapedics’ product, i-FACTOR®, is FDA approved for single level cervical spinal fusions in the United States. Cerapedics’ next-generation product is currently being evaluated for use in lumbar interbody fusion through ASPIRE, a pivotal IDE study, and has been granted a Breakthrough Device Designation by the FDA. Cerapedics is headquartered in Westminster, CO.

Elevation Spine is a medical device company with a proprietary technology platform, Saber Technology, which is an advanced and differentiated approach to fusion. Saber Technology was designed to improve patient outcomes while providing surgeons with a high-tech, yet simple approach to spinal fusion procedures. The first FDA cleared Saber Technology product, Saber-C, is comprised of a zero-profile anterior cervical plate that accepts multiple spacer material and fixation options and provides a proprietary single-step integrated-fixation. Traditional fusion technologies utilize a plate and screws to fixate the spine during a fusion procedure. Alternatively, Saber-C’s robust and versatile implant offering utilizes a unique curved spike device which eliminates the large working space that a straight screw requires, therefore minimizing incision size and simplifying the surgical technique. As a result, the Elevation Spine fusion procedure is highly efficient while remaining minimally invasive.

Easing the burden of spine-related pain Spine-related pain is taking a huge toll on our society: more days in bed, more days off work, and at a greater financial cost to westernized healthcare than any other condition. In fact, today, nearly 1 in 5 spinal fusion surgeries result in a non-union of the bones in the spine.

Outcome driven innovation Disruptive innovation is in our DNA. It’s the heartbeat of our organization. We innovate for the benefit of the surgeon, provider and patient—driven by our vision and shared mindset—ultimately, delivering clinical, operational and financial outcomes. We partner with leading surgeons to transform surgery, support providers by optimizing products and services to advance care, and design an enhanced experience that changes patient lives.

Helping restore mobility and quality of life to patients. At SeaSpine®, we believe spine surgery patients should easily benefit from the most advanced scientific knowledge and technology available.

SI-BONE, Inc. is a medical device company dedicated to solving musculoskeletal disorders of the sacropelvic anatomy. Founded in 2008, the company pioneered the surgical treatment of the SI joint with the iFuse Implant System. Current products, including applications in spinal deformity and SI joint trauma, have expanded the company’s scope within the sacropelvic space. The iFuse Implant’s unique triangular geometry provides immediate stabilization, while the 3D printed porous surface facilitates osteointegration. With more than 45,000 procedures, 2,000+ treating surgeons and 80+ publications, iFuse is the leading choice in the surgical treatment of sacropelvic disorders.

Our VITA Values “Vita” means life — and the lives of the patients and healthcare professionals we serve are at the core of everything we do. VIP Customer Care Promise At Theragen, people come first. Whether you’re a patient, caregiver, or healthcare provider, we go above and beyond to ensure satisfaction at every interaction, with everyone, period. Innovation From next-gen digital engagement to new energy applications that patients can use at home, we’re always pursuing technology advancements that benefit our customers and our company. Tenacity We’re a team of problem solvers. We work hard to ensure every patient can access our solutions, regardless of their financial situation — and to keep things running smoothly and efficiently for all. Authenticity Our solutions are supported by the highest levels of clinical evidence. Our company is built on trust. And our team is motivated by genuine, shared empathy for those we serve each day.

Adcura™ is a medical device company focusing on PRECISE PATIENT SOLUTIONS that improve the quality of life for patient’s suffering from spine related issues while addressing current surgical inefficiencies.

ATEC is more than a medical technology company. We are an Organic Innovation Machine™ that is focused on Revolutionizing the Approach to Spine Surgery. We are committed to creating clinical distinction by developing new approaches to treat the various pathologies to ultimately achieve the goals of spine surgery. Our ultimate vision is to become The Standard-Bearer in Spine.

Decades in the making, Barricaid is the only FDA-approved device designed to close large defects in the annulus. Barricaid allows you to preserve more of your patient’s disc while reducing their risk of reherniation and reoperation. A Level I RCT (randomized controlled trial) of 554 patients showed an approximate 50% reduction in reherniation and reoperative recurrence starting at the 90-day mark and running through 36 months post-surgery.

Everything we do converges at the critical intersection where products that save and sustain lives meet the healthcare professionals and caregivers who make it all happen. Now, we support more patients through every point of their journey, with a broad set of solutions that empowers healthcare professionals to deliver smarter, more personalized care. Together, we are transforming healthcare with bold innovations that will help us realize our shared promise to improve care for all.

Centinel Spine continues its leadership in total disc replacement—now the only company with a portfolio that allows matching the disc to meet surgeon preference and patient needs.

Eminent spine focuses on anticipating and adjusting to the ever-changing needs and wants of the industry in order to bring you the best products on the market.

Comprehensive spinal surgery devices and solutions We help surgeons deliver better outcomes for patients. For two decades we have continued to release increasingly innovative surgical technologies, including MIS Ultra®, the newest addition to our highly differentiated suite of spinal surgery devices and technologies.

Spinal Simplicity, LLC was founded in 2008 by Dr. Harold Hess, a practicing neurosurgeon, and Todd Moseley, an entrepreneur with over 30 years’ experience in orthopedics. The company began focusing on minimally invasive Lateral Approach lumbar fusion technology. In May 2011, Spinal Simplicity received CE approval for its initial product, the Minuteman, as well as ISO 13485 certification for its quality management system. In January 2015, FDA 510(k) clearance was granted for the Minuteman G3 device. Spinal Simplicity was granted FDA 510(k) clearance for the HA Minuteman® G3 in August of 2015 and for the HA Minuteman® G3R in January of 2017. On December 17, 2021, Spinal Simplicity announced the much-anticipated FDA clearance of a new Indication for Use (IFU) for its Minuteman family of implants, Lumbar Spinal Stenosis. These are significant milestones that allow Spinal Simplicity to compete in the fast-growing, minimally invasive spine market. Many have asked the question, “Why the name Minuteman?” As a proud American company, we chose to incorporate history into our mission and vision! Minutemen were civilian colonists who independently formed militia companies self-trained in weaponry, tactics, and military strategies, comprising the American colonial partisan militia during the American Revolutionary War. They were known for being ready at a minute’s notice, hence the name. Just like the minutemen of history, Team Minuteman is highly mobile, dedicated, and able to assemble quickly. We strive daily to be a leader in innovative, simplified surgical solutions, championing uncompromising quality with products proudly made in the USA.

Our mission is to honor the gift of donation, by allowing our patients to live as full, and complete a life as possible. At Xtant, quality is first in everything we do. Our products and services will meet regulatory requirements through our effective quality system.