- Puncture without establish infection
- prophylactic antibiotic treatment for a recent puncture wound with no clear evidence of infection is controversial
- Clear evidence of infection
- ceftazidime or cefepime antiobiotic therapy
- for established infection initial antibiotics should include ceftazidime or cefepime
- alternatives include ciprofloxacin (in adults), imipenem, cilastin, 3rd generation cephalosporin
- surgical debridement
- indicated in deep infection with osteomyelitis that is not improving with oral antibiotics
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