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onset most often by age 30.
0%
3/743
a temporary state of neuronal and axonal derangement.
2%
18/743
manifestations of affect such as apathy, irritability, and suicidal ideation.
94%
695/743
absence of gross pathological brain changes upon autopsy.
3%
19/743
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CTE is a neurodegenerative disease that occurs years or decades after recovery from acute or postacute effects of head trauma. The exact relationship between concussion and CTE is not entirely clear; however, early behavioral manifestations of CTE have been described by family and providers to include apathy, irritability, and suicidal ideation. For some patients, cognitive difficulty such as poor episodic memory and executive function may be the first signs of CTE. Onset most often occurs in midlife after athletes have completed their sports careers, with mean age of onset at 42 years. The effects on the brain are degenerative, leading to a permanent state of derangement. Autopsy findings demonstrate multiple gross pathological findings. The condition is more common among contact athletes.
2.8
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