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Femoral head scratching from third-body debris
7%
94/1289
Edge loading and associated loss of fluid-film lubrication
36%
466/1289
Increased macrophage reactivity to <em>Propionibacterium acnes (P. acnes)</em>
2%
26/1289
Increased lymphocyte reactivity to nickel ion
54%
692/1289
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Several reports have documented the development of pseudotumors in patients undergoing MOMHRA. The incidence of pseudotumor is likely lower than 1% in this group of patients. Patients usually are asymptomatic. Recent investigation suggests that pseudotumors occur more often with increased wear attributable to edge loading. Edge loading most commonly results from abnormal contact stresses that occur in the setting of a malpositioned cup orientation. Lymphocyte reactivity to cobalt, chromium, and nickel did not significantly differ in patients with pseudotumors compared to patients without pseudotumors. Macrophage reactivity to P. acnes would be present in the setting of infection, but not present in the development of pseudotumors.
1.3
(26)
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